Yaws is a non-venereal tropical infectious disease caused by the organism Treponema pertenue.[1] This organism is closely related to the. Yaws is an infectious tropical disease caused by the spirochete (spiral shaped) bacterium known as Treponema pertenue. The disease presents in three stages . Yaws is a tropical disease characterized by a primary cutaneous lesion, followed by a granulomatous skin eruption, and sometimes by late destructive lesions of.

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Unfortunately, due to many factors, some changeable and others not, this is no longer the case and the infections are increasing again just when they were thought to have been almost eliminated. Prognosis Prognosis with treatment is very good if caught during primary or secondary stages. Most often the diagnosis is made clinically. About three quarters fframbesia people affected are children under 15 years of age, with the greatest incidence in children 6—10 years old.

Epub Sep 4. Radiologic abnormalities reveal dactylitis and osteoperiostitis. Causes Yaws is an infectious disease caused by a spiral-shaped bacterium spirochete known as Treponema pertenue.

What is Yaws Disease? – End Yaws

The genetic analysis of the yaws’ causative bacteria— Treponema pallidum pertenue —has led to the conclusion that yaws is the most ancient of the four known Treponema diseases. To prevent its spread, affected children cannot go to school or play with other children. These have a chance of false-positive results but good sensitivity and are useful as markers to confirm cure with falling titers following treatment.

Pimple-like bumps appear on the skin; they are small, reddish, and patchy. Radius, ulna, and phalanges are the most frequent. Efficacy of a targeted oral penicillin-based frambeesia control program amoung children living in rural South America.

Tropical Medicine Central Resource

This dosing is lower than used in venereal syphilis. PMC ] [ PubMed: Government funding, and some supported by private industry, are posted on this government web site. The last clinical case in India was reported in and the last latent case in Painful skin and bone nodules may impair joint function and mobility.


Trop Med Int Health. However, no evidence exists of cross-transmission between human beings and primates, but more research is needed to discount the possibility of a yaws animal reservoir in non-human primates. Wikimedia Commons has media related to Yaws.

Each year it affects more thanchildren between the ages of 5 and 15 in 13 endemic countries of West Africa, Southeast Asia and the Pacific.

What is Yaws Disease?

This book is distributed under the terms of the Creative Commons Attribution 4. Luke Maxfield ; Jonathan S.

Bacterium-related cutaneous conditions Syphilis Infectious diseases frambesai eradication efforts Neglected diseases Tropical diseases. Yaws is an infectious tropical disease caused by the spirochete spiral shaped bacterium known as Treponema pertenue. Archived PDF from the original on frmabesia This is due to the host immune response against the organism.

Azithromycin is an antibiotic used for infections of the respiratory tract, very common in our pharmacies. Unlike syphilis, yaws is neither sexually transmitted nor transmitted from mother to baby.

The latter requires the presence of antibodies with one being a non-treponemal antigen and the other a treponemal antigen. From Wikipedia, the free encyclopedia. Clinically, the disease is comprised of distinct stages similar to venereal syphilis with cutaneous findings in early stages, and after a latent period, late yaws may manifest as gummatous nodules, scarring, and destructive bone lesions.

Community participation eliminates yaws in Ecuador. The first unambiguous description of yaws was made by the Dutch physician Willem Piso. It is caused by the bacteria Treponema pallidum pertenue and, if left untreated, can pass into the bones and cause inflammation farmbesia severe disfigurements. Lesions are also responsive to azithromycin.


Retrieved 5 August About News Events Contact. Dissemination of the organism through lymphatic or hematogenous spread is responsible for the progression of the disease. Yaws has required global coordination, as endemic areas often are under-equipped for diagnosis or treatment. For many years it has been customary to fdambesia nonvenereal syphilis and yaws as separate entities. By using this site, you agree to the Terms of Use frmabesia Privacy Policy. In between primary and secondary or secondary and tertiary stages, a latent period occurs.

Although once common in endemic areas, global efforts to eradicate the disease through penicillin and azithromycin have made the tertiary disease a rarity and significantly decreased global hropical.

Based on symptoms, blood antibody tests, polymerase chain reaction [4]. Yaws is very common in tropical areas of the world but it is not known in the United States. It is often difficult, if not impossible, trlpical the radiologist to fambesia between endemic syphilis and yaws. Yaws was clearly described in among African slaves by Thomas Sydenham in his epistle on venereal diseasesalthough he thought that it was the same disease as syphilis. Beers MH, Berkow R. It occurs in children younger than 15 years of age.

This painful skin lesion from sexual contact that may cause genital and non-genital lesions in areas where endemic. Over the next 20 years, the annual incidence fell from However, cutaneous manifestations of other diseases may have significant overlap. Treponema pallidum pertenue spread by direct contact [4]. By the number of cases was Research on tropical diseases such as yaws is ongoing.